Next available departures

Next departures for Brno to Prague on September 29
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Wi‑Fi Toilet Power outlets	8:10pm	Hotelu Grand	2h 35m	10:45pm	Prague (Central Bus Station Florenc)	Cheapest
	Toilet Power outlets	9:20pm	Hotelu Grand	2h 20m	11:40pm	Florenc	Fastest
	Toilet Power outlets	5:00pm	Hotelu Grand	2h 55m	7:55pm	Florenc	No tags
	Wi‑Fi Toilet Power outlets	8:50pm	Hotelu Grand	3h 15m	12:05am	PRG Airport	No tags
Ceske Drahy		6:20pm	Hlavní nádraží	3h 35m	9:55pm	Hlavní nádraží	No tags
	Toilet Power outlets	6:00pm	Hotelu Grand	2h 30m	8:30pm	Florenc	No tags
	Wi‑Fi Toilet Power outlets	3:40pm	Hotelu Grand	2h 50m	6:30pm	Prague (Central Bus Station Florenc)	No tags
	Wi‑Fi Toilet Power outlets	4:10pm	Hotelu Grand	2h 55m	7:05pm	Prague (Central Bus Station Florenc)	No tags

Next departures for Brno to Prague on September 30
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Wi‑Fi Toilet Power outlets	6:10pm	Hotelu Grand	2h 30m	8:40pm	Prague (Central Bus Station Florenc)	Cheapest
	Toilet Power outlets	9:20pm	Hotelu Grand	2h 20m	11:40pm	Florenc	Fastest
Vlak společnosti Gepard Express		1:40am	bus station Grand	2h 30m	4:10am	Vaclav Havel Airport Prague	No tags
		2:15am	Brno [*CZ],,Benešova tř.hotel GRAND, platform 4, Brno	2h 25m	4:40am	Praha Hlavní nádraží	No tags
	Toilet Power outlets	1:40am	Hotelu Grand	2h 30m	4:10am	PRG Airport	No tags
	Wi‑Fi Toilet Power outlets	2:55am	Hotelu Grand	3h 5m	6:00am	PRG Airport	No tags
Vlak společnosti Gepard Express		12:00pm	bus station Grand	2h 25m	2:25pm	Vaclav Havel Airport Prague	No tags
	Toilet Power outlets	3:30am	Hotelu Grand	2h 30m	6:00am	Florenc	No tags

Next departures for Brno to Prague on October 1
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Wi‑Fi Toilet Power outlets	9:40am	Hotelu Grand	2h 55m	12:35pm	Prague (Central Bus Station Florenc)	Cheapest
	Toilet Power outlets	9:20pm	Hotelu Grand	2h 20m	11:40pm	Florenc	Fastest
		2:15am	Brno [*CZ],,Benešova tř.hotel GRAND, platform 4, Brno	2h 25m	4:40am	Praha Hlavní nádraží	No tags
Vlak společnosti Gepard Express		8:00am	bus station Grand	2h 25m	10:25am	Vaclav Havel Airport Prague	No tags
RegioJet + RegioJet	Toilet Power outlets	2:00am	Hotelu Grand	3h 46m	5:46am	Hlavní nádraží	No tags
	Wi‑Fi Toilet Power outlets	2:55am	Hotelu Grand	3h 5m	6:00am	PRG Airport	No tags
Vlak společnosti Gepard Express		12:00pm	bus station Grand	2h 25m	2:25pm	Vaclav Havel Airport Prague	No tags
	Toilet Power outlets	5:30am	Hotelu Grand	2h 55m	8:25am	Florenc	No tags

Next departures for Brno to Prague on October 2
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Wi‑Fi Toilet Power outlets	1:30am	Hotelu Grand	2h 35m	4:05am	Prague (Central Bus Station Florenc)	Cheapest
	Toilet Power outlets	9:20pm	Hotelu Grand	2h 20m	11:40pm	Florenc	Fastest
Vlak společnosti Gepard Express		1:40am	bus station Grand	2h 30m	4:10am	Vaclav Havel Airport Prague	No tags
		2:15am	Brno [*CZ],,Benešova tř.hotel GRAND, platform 4, Brno	2h 25m	4:40am	Praha Hlavní nádraží	No tags
	Toilet Power outlets	1:40am	Hotelu Grand	2h 30m	4:10am	PRG Airport	No tags
	Wi‑Fi Toilet Power outlets	2:55am	Hotelu Grand	3h 5m	6:00am	PRG Airport	No tags
Vlak společnosti Gepard Express		6:00am	bus station Grand	2h 25m	8:25am	Vaclav Havel Airport Prague	No tags
	Toilet Power outlets	3:30am	Hotelu Grand	2h 30m	6:00am	Florenc	No tags

Next departures for Brno to Prague on October 3
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Wi‑Fi Toilet Power outlets	4:10pm	Hotelu Grand	2h 55m	7:05pm	Prague (Central Bus Station Florenc)	Cheapest
	Toilet Power outlets	9:20pm	Hotelu Grand	2h 20m	11:40pm	Florenc	Fastest
Vlak společnosti Gepard Express		1:40am	bus station Grand	2h 30m	4:10am	Vaclav Havel Airport Prague	No tags
		2:15am	Brno [*CZ],,Benešova tř.hotel GRAND, platform 4, Brno	2h 25m	4:40am	Praha Hlavní nádraží	No tags
	Toilet Power outlets	1:40am	Hotelu Grand	2h 30m	4:10am	PRG Airport	No tags
	Wi‑Fi Toilet Power outlets	2:55am	Hotelu Grand	3h 5m	6:00am	PRG Airport	No tags
Vlak společnosti Gepard Express		10:00am	bus station Grand	2h 25m	12:25pm	Vaclav Havel Airport Prague	No tags
	Toilet Power outlets	3:30am	Hotelu Grand	2h 30m	6:00am	Florenc	No tags

Next departures for Brno to Prague on October 4
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Toilet Power outlets	5:30am	Hotelu Grand	2h 55m	8:25am	Florenc	Cheapest
	Toilet Power outlets	9:20pm	Hotelu Grand	2h 20m	11:40pm	Florenc	Fastest
Vlak společnosti Gepard Express		1:40am	bus station Grand	2h 30m	4:10am	Vaclav Havel Airport Prague	No tags
		2:15am	Brno [*CZ],,Benešova tř.hotel GRAND, platform 4, Brno	2h 25m	4:40am	Praha Hlavní nádraží	No tags
	Toilet Power outlets	1:40am	Hotelu Grand	2h 30m	4:10am	PRG Airport	No tags
	Wi‑Fi Toilet Power outlets	2:55am	Hotelu Grand	3h 5m	6:00am	PRG Airport	No tags
Vlak společnosti Gepard Express		10:00am	bus station Grand	2h 25m	12:25pm	Vaclav Havel Airport Prague	No tags
	Toilet Power outlets	3:30am	Hotelu Grand	2h 30m	6:00am	Florenc	No tags

Next departures for Brno to Prague on October 5
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Wi‑Fi Toilet Power outlets	6:40am	Hotelu Grand	2h 55m	9:35am	Prague (Central Bus Station Florenc)	Cheapest
	Toilet Power outlets	9:20pm	Hotelu Grand	2h 20m	11:40pm	Florenc	Fastest
Vlak společnosti Gepard Express		1:40am	bus station Grand	2h 30m	4:10am	Vaclav Havel Airport Prague	No tags
		2:15am	Brno [*CZ],,Benešova tř.hotel GRAND, platform 4, Brno	2h 25m	4:40am	Praha Hlavní nádraží	No tags
	Toilet Power outlets	1:40am	Hotelu Grand	2h 30m	4:10am	PRG Airport	No tags
	Wi‑Fi Toilet Power outlets	2:55am	Hotelu Grand	3h 5m	6:00am	PRG Airport	No tags
Vlak společnosti Gepard Express		10:00am	bus station Grand	2h 25m	12:25pm	Vaclav Havel Airport Prague	No tags
	Toilet Power outlets	3:30am	Hotelu Grand	2h 30m	6:00am	Florenc	No tags

Next departures for Brno to Prague on October 6
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Wi‑Fi Toilet Power outlets	1:30am	Hotelu Grand	2h 35m	4:05am	Prague (Central Bus Station Florenc)	Cheapest
	Toilet Power outlets	9:20pm	Hotelu Grand	2h 20m	11:40pm	Florenc	Fastest
Vlak společnosti Gepard Express		1:40am	bus station Grand	2h 30m	4:10am	Vaclav Havel Airport Prague	No tags
		2:15am	Brno [*CZ],,Benešova tř.hotel GRAND, platform 4, Brno	2h 25m	4:40am	Praha Hlavní nádraží	No tags
	Toilet Power outlets	1:40am	Hotelu Grand	2h 30m	4:10am	PRG Airport	No tags
	Wi‑Fi Toilet Power outlets	2:55am	Hotelu Grand	3h 5m	6:00am	PRG Airport	No tags
Vlak společnosti Gepard Express		6:00am	bus station Grand	2h 25m	8:25am	Vaclav Havel Airport Prague	No tags
	Toilet Power outlets	3:30am	Hotelu Grand	2h 30m	6:00am	Florenc	No tags

Last refresh of the prices: Today at 12:17 PM CEST.

Compare 2 ways to go from Brno to Prague

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Prague. The journey takes about 2 hours 35 minutes, and with fares starting at just COP 36,469, it presents an excellent value for a comfortable ride.

64bus per day

2h 35mAverage Duration

188 kmDistance

5kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average PriceCOP 36,469 - COP 142,421	Average Duration2h 35m	CO₂ emissions 5kg CO₂e
Train	Average PriceCOP 44,343 - COP 253,036	Average Duration2h 55m	CO₂ emissions 4kg CO₂e

Bus stations and stops in Brno and Prague

Stops in Brno

A
Hotelu Grand
Benešova 603/2, Brno-město, 602 00 Brno-Brno-střed, Czech Republic
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B
Hlavní nádraží
Nádražní 418/1, Brno-město, 602 00 Brno-Brno-střed, Czechia
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C
Brno Bus Station
Brno Bus Station, ÚAN Zvonařka, 602 00 Brno-střed, Czechia
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D
ÚAN Zvonařka
Zvonařka 411, Trnitá, 602 00 Brno-Brno-střed, Czech Republic
Visit page
E
Židenice
Lazaretní 610/11, 615 00 Brno-Brno-Židenice, Czechia
Visit page
F
Vídeňská 98
Vídeňská 98, 619 00 Brno-jih, Czechia

Stops in Prague

A
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic
B
Tomíčkova
Tomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
Visit page
C
PRG Airport
Aviatická, 161 08, Praha 6, Czechia
Visit page
D
Černý Most
Chlumecká, 198 00 Praha 20, Czech Republic
Visit page
E
Florenc
Křižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
Visit page
F
Hlavní nádraží
300/8 Wilsonova, 110 00 Praha, Czechia
Visit page

Compare companies

FlixBus

3.5/515,971 reviews

Staff4.2

Timeliness4.0

Cleanliness4.1

Wi‑Fi2.7

RegioJet

4.1/51,113 reviews

Staff4.5

Timeliness4.0

Cleanliness4.3

Wi‑Fi3.7

A-Express

Slovak Lines

4.5/5187 reviews

Staff4.8

Timeliness4.9

Cleanliness5.0

Wi‑Fi4.3

IC Bus

4.5/520 reviews

Staff5.0

Timeliness5.0

Cleanliness5.0

Gepard Express

Monobus

2.5/54 reviews

Staff5.0

Timeliness3.8

Cleanliness2.5

Wi‑Fi2.5

CZ bus companies:FlixBus, BlaBlaCar Bus, Deutsche Bahn, Sindbad, Ecolines, KLR Bus, RegioJet

Frequently asked questions about travelling from Brno to Prague by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Brno to Prague?
The cheapest bus tickets from Brno to Prague start from COP 36,469. The average price for this route is around COP 50,041. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Brno to Prague?
The average bus travel time from Brno to Prague is 2h 35m, covering a distance of 188 km. The quickest bus can get you there in 1h 25m and is operated by FlixBus.
Which bus companies service the Brno to Prague route?
Several major bus companies operate on this route with 64 buses available per day, including services from FlixBus, RegioJet, A-Express, Slovak Lines, IC Bus, Gepard Express, Monobus.
What are the earliest and latest departure times for the bus from Brno to Prague?
The earliest bus departs from Brno to Prague at 1:30am. And the latest bus departs at 11:59pm.
What are the CO₂ emissions for the bus trip from Brno to Prague?
A bus trip from Brno to Prague generates an estimated 4.6891750000000005 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Brno to Prague?
According to Busbud customers, the highest-rated bus company on this route is Slovak Lines, with an average rating of 4.5 out of 5 stars based on 187 reviews.
Which bus company has the best Wi-Fi from Brno to Prague?
Based on Busbud reviews, the bus company Slovak Lines has the highest Wi-Fi rating with a score of 4.3.
Which bus company has the best on-time performance from Brno to Prague?
According to Busbud traveller reviews, the most punctual bus company on this route is IC Bus, with a punctuality rating of 5.0 out of 5 stars.
Which bus company has the cleanest buses from Brno to Prague?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is IC Bus, with a cleanliness rating of 5.0 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

09-27

COP 50,525

09-28

COP 60,298

Today

COP 22,068

09-30

COP 22,068

10-01

COP 22,068

10-02

COP 32,118

10-03

COP 22,068

10-04

COP 32,118

The cheapest trip from Brno to Prague was searched and found on Sep 29, 2026 with a price of COP 22,068

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Brno to Prague, as early as possible.

You can expect to pay from COP 22,068 to COP 231,417 for a bus ticket from Brno to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at COP 22,068 which is on 2026-09-30.