Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Boston (South Station) | Indianapolis Bus Station | Cheapest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Boston (South Station) | Downtown Transit Center | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Boston (South Station) | Indianapolis Bus Station | No tags | ||||
| Bus | Boston (South Station) | Indianapolis Bus Station | No tags | ||||
 | Bus | Brookline | Downtown Transit Center | No tags |
Last refresh of the prices: Today at 5:05 PM EDT.
Compare 2 ways to go from Boston to Indianapolis
Among the sustainable travel choices, the Bus stands out as a good way to reach Indianapolis. The journey takes about 1 day, 1 hour 40 minutes and with fares starting at just $101, it presents an excellent value for a comfortable ride.
Where are the popular stops in Boston and Indianapolis?
Stops in Boston
- A
Back Bay Station
145 Dartmouth St, Boston, MA 02116, USA - B
North Station
100 Legends Way, Boston, MA 02114, USA - C
Riverside Bus Station
335 Grove St, Auburndale, MA 02466 - D
Prudential MBTA Station
220 Huntington Ave, Boston, MA 02115, USA - E
Copley MBTA Station
650 Boylston St, Boston, MA 02116, USA - F
Long Wharf
66 Long Wharf, Boston, MA 02110, USA
Compare bus companies
Frequently asked questions about traveling from Boston, MA, US to Indianapolis by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Boston to Indianapolis?
The cheapest bus tickets from Boston to Indianapolis start from $101. The average price for this route is around $145. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Boston to Indianapolis?
The average bus trip duration from Boston to Indianapolis is 1d 1h, covering a distance of 803 miles (1295 km). The quickest bus can get you there in 22h 35m and is operated by Greyhound.
Which bus companies service the Boston to Indianapolis route?
What is the earliest and latest departure time for the bus from Boston to Indianapolis?
The earliest bus departs from Boston to Indianapolis at 1:30am. And the latest bus departs at 10:00pm.
What are the CO₂ emissions for the bus trip from Boston to Indianapolis?
A bus trip from Boston to Indianapolis generates an estimated 32.3517 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Boston to Indianapolis?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 12712 reviews.
Which bus company has the best Wi-Fi from Boston to Indianapolis?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Boston to Indianapolis?
According to Busbud traveler reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Boston to Indianapolis?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Boston, MA, US to Indianapolis was searched and found on Jun 11, 2026 with a price of $126To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Boston, MA, US to Indianapolis, as early as possible.
You can expect to pay from $126 to $294 for a bus ticket from Boston, MA, US to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at $126 which is on 2026-06-11.
Usually Greyhound, FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Boston, MA, US to Indianapolis?
The Bus is the cheapest travel choice for this destination
