Previously seen trips

Next departures for Frederick to Florence on August 23
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location
FlixBus + Greyhound	Bus	10:25am	Frederick	19h 20m	5:45am	Florence, SC
Greyhound + FlixBus	Bus	11:40pm	Frederick	1d	12:05am	Florence, SC
	Bus	11:40pm	Frederick	12h 19m	11:59am	Bus station
FlixBus + Greyhound	Bus	10:25am	Frederick	19h 20m	5:45am	Florence, SC
Greyhound + FlixBus	Bus	11:40pm	Frederick	1d	12:05am	Florence, SC

Get from Frederick to Florence

This route is served by bus only

The journey takes about 19 hours 20 minutes and with fares starting at just COP 303,000, it presents an excellent value for a comfortable ride.

2bus per day

19h 20mAverage Duration

383 milesDistance

15kgCO₂ emissions

Compare companies

Amtrak

4.1/56,452 reviews

Staff4.7

Timeliness3.8

Cleanliness4.5

Wifi3.6

Greyhound

3.5/588,079 reviews

Staff3.6

Timeliness3.0

Cleanliness3.4

Wifi2.5

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies:FlixBus, Greyhound, Futura, Chihuahuenses, Tufesa, Elite, Adirondack Trailways

Frequently asked questions about traveling from Frederick to Florence, SC, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Frederick to Florence?
The cheapest bus tickets from Frederick to Florence start from COP 303,000. The average price for this route is around COP 331,433. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Frederick to Florence?
The average bus trip duration from Frederick to Florence is 19h 20m, covering a distance of 383 miles (618 km). The quickest bus can get you there in 12h 19m and is operated by Greyhound.
Which bus companies service the Frederick to Florence route?
Several major bus companies operate on this route with 2 buses available per day, including services from Amtrak, Greyhound.
What is the earliest and latest departure time for the bus from Frederick to Florence?
The earliest bus departs from Frederick to Florence at 10:25am. And the latest bus departs at 11:40pm.
What are the CO₂ emissions for the bus trip from Frederick to Florence?
A bus trip from Frederick to Florence generates an estimated 15.427975 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Frederick to Florence?
According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 6437 reviews.
Which bus company has the best Wi-Fi from Frederick to Florence?
Based on reviews on Busbud, the bus company Amtrak has the best Wi-Fi rating with a score of 3.6.
Which bus company has the most timely service from Frederick to Florence?
According to Busbud traveler reviews, the most timely bus company on this route is Amtrak, with a punctuality rating of 3.8 out of 5 stars.
Which bus company has the cleanest buses from Frederick to Florence?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.