Next available departures

Next departures for Isernia to Rome on July 14
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
11:35am	Isernia	2h 25m	2:00pm	Rome Tiburtina Bus Station	Cheapest
8:38am	Isernia	2h 14m	10:52am	Termini	Fastest
7:08am	Isernia	3h 10m	10:18am	Termini	No tags
6:15pm	Isernia	6h 45m	1:00am	Rome Fiumicino Airport	No tags
3:03pm	Isernia	2h 27m	5:30pm	Termini	No tags
3:20pm	Isernia	5h	8:20pm	Termini	No tags
6:00pm	Isernia	2h 25m	8:25pm	Termini	No tags

Last refresh of the prices: Today at 9:38 PM CEST.

Compare 2 ways to go from Isernia to Rome

We recommend taking the train

Among the sustainable travel choices, the Train stands out as a good way to reach Rome. The journey takes about 2 hours 25 minutes and with fares starting at just ₹1,769, it presents an excellent value for a comfortable ride.

4train per day

2h 25mAverage Duration

92 milesDistance

4kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price₹1,534 - ₹13,143	Average Duration6h 45m	CO₂ emissions 4kg CO₂e
Train	Average Price₹1,769 - ₹2,112	Average Duration2h 25m	CO₂ emissions 4kg CO₂e

Bus stations and stops in Isernia and Rome

Stops in Isernia

A
Isernia
Piazza della Repubblica, 9, 86170 Isernia IS, Italy
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Stops in Rome

A
Termini
Piazza dei Cinquecento 1, 00185 Roma RM, Italy
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B
Rome Tiburtina Bus Station
Largo Guido Mazzoni, 3, 00162 Roma, Italy
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C
Rome Fiumicino Airport (FCO), Train station
Fiumicino Aeroporto, 00054 Fiumicino RM, Italy
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D
Roma S. Pietro
Roma S.Pietro, 00165 Roma RM, Italy
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E
Roma Trastevere
Roma Trastevere Railway Station, 00152 Roma RM, Italy
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F
Rome Ciampino Airport
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Compare companies

FlixBus

3.5/513,005 reviews

Staff4.2

Timeliness4.0

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Trenitalia

4.0/565 reviews

Staff4.7

Timeliness4.7

Cleanliness4.7

Wifi2.8

Companies in IT:FlixBus, Trenitalia, BlaBlaCar Bus, Deutsche Bahn, ALSA, FlixTrain, Rede Expressos, RegioJet, Trenitalia, Deutsche Bahn ICE, Sindbad, NS Nederlandse Spoorwegen, MarinoBus, Italo

Frequently asked questions about traveling from Isernia to Rome by bus or train

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is a ticket from Isernia to Rome?
The cheapest tickets from Isernia to Rome start from ₹1,534. The average price for this route is around ₹3,334. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the ride from Isernia to Rome?
The average trip duration from Isernia to Rome is 4h 35m, covering a distance of 96 miles (154 km). The quickest vehicle can get you there in 2h 7m and is operated by Trenitalia.
Which companies service the Isernia to Rome route?
Several major companies operate on this route with 3 trips available per day, including services from FlixBus, Trenitalia.
What is the earliest and latest departure time from Isernia to Rome?
The earliest trip departs from Isernia to Rome at 7:08am. And the latest trip departs at 8:35pm.
What are the CO₂ emissions for the trip from Isernia to Rome?
A trip from Isernia to Rome generates an estimated 3.8424500000000004 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best company from Isernia to Rome?
According to Busbud customers, the highest-rated company on this route is Trenitalia, with an average rating of 4.0 out of 5 stars based on 64 reviews.
Which company has the best Wi-Fi from Isernia to Rome?
Based on reviews on Busbud, the company Trenitalia has the best Wi-Fi rating with a score of 2.8.
Which company has the most timely service from Isernia to Rome?
According to Busbud traveler reviews, the most timely company on this route is Trenitalia, with a punctuality rating of 4.7 out of 5 stars.
Which company has the cleanest vehicles from Isernia to Rome?
According to Busbud traveler reviews, the company with the cleanest vehicles on this route is Trenitalia, with a cleanliness rating of 4.7 out of 5 stars.

Find cheapest prices for buses and trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

07/11

₹1,360

07/12

₹1,665

Today

₹1,606

07/14

₹1,549

07/15

₹1,360

07/16

₹1,437

07/17

₹1,418

07/18

₹1,418

The cheapest trip from Isernia to Rome was searched and found on Jul 11, 2026 with a price of ₹1,360

To save money and be sure you have the best seat, it's a good idea to buy your bus and train tickets from Isernia to Rome, as early as possible.

You can expect to pay from ₹1,360 to ₹8,558 for a bus or train ticket from Isernia to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at ₹1,360 which is on 2026-07-15.