Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Paducah Bus Station | Bus station | Cheapest | ||||
 | Bus | Paducah Bus Station | Florence, SC | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Paducah Bus Station | Bus station | No tags |
Last refresh of the prices: Yesterday at 4:11 PM CDT.
Get from Paducah to Florence
The journey takes about 1 day, 6 hours 25 minutes and with fares starting at just ₪375, it presents an excellent value for a comfortable ride.
Where are the popular stops in Paducah and Florence?
Stops in Florence
- A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA - B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Compare bus companies
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Paducah to Florence, SC, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Paducah to Florence?
The cheapest bus tickets from Paducah to Florence start from ₪375. The average price for this route is around ₪520. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Paducah to Florence?
The average bus trip duration from Paducah to Florence is 1d 6h, covering a distance of 532 miles (858 km). The quickest bus can get you there in 20h 5m and is operated by FlixBus.
Which bus companies service the Paducah to Florence route?
Several major bus companies operate on this route with 3 buses available per day.
What is the earliest and latest departure time for the bus from Paducah to Florence?
The earliest bus departs from Paducah to Florence at 3:00am. And the latest bus departs at 6:05am.
What are the CO₂ emissions for the bus trip from Paducah to Florence?
A bus trip from Paducah to Florence generates an estimated 21.4319 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Paducah to Florence, SC, US was searched and found on Jun 11, 2026 with a price of ₪314To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Paducah to Florence, SC, US, as early as possible.
You can expect to pay from ₪314 to ₪314 for a bus ticket from Paducah to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at ₪314 which is on 2026-06-11.
