Next departures for Palermo to Syracuse on September 25
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Terminal Bus Palermo
Syracuse bus station
Cheapest
Bus
Palermo Oreto Orsi
Syracuse bus station
Fastest
Bus
Terminal Bus Palermo
Syracuse bus station
No tags
Bus
Wifi
Toilet
Power outlets
Terminal Bus Palermo
Terminal Interbus
No tags
Bus
Terminal Bus Palermo
Syracuse bus station
No tags
Bus
Terminal Bus Palermo
Syracuse bus station
No tags
Bus
Palermo Oreto Orsi
Syracuse bus station
No tags
Bus
Palermo Oreto Orsi
Syracuse bus station
No tags
Next departures for Palermo to Syracuse on September 26
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Terminal Bus Palermo
Syracuse bus station
Cheapest
Bus
Palermo Oreto Orsi
Syracuse bus station
Fastest
Bus
Terminal Bus Palermo
Syracuse bus station
No tags
Bus
Wifi
Toilet
Power outlets
Terminal Bus Palermo
Terminal Interbus
No tags
Bus
Terminal Bus Palermo
Syracuse bus station
No tags
Bus
Terminal Bus Palermo
Syracuse bus station
No tags
Bus
Palermo Oreto Orsi
Syracuse bus station
No tags
Bus
Palermo Oreto Orsi
Syracuse bus station
No tags
Next departures for Palermo to Syracuse on September 27
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Terminal Bus Palermo
Syracuse bus station
Cheapest
Bus
Palermo Oreto Orsi
Syracuse bus station
Fastest
Bus
Terminal Bus Palermo
Syracuse bus station
No tags
Bus
Wifi
Toilet
Power outlets
Terminal Bus Palermo
Terminal Interbus
No tags
Bus
Terminal Bus Palermo
Syracuse bus station
No tags
Bus
Terminal Bus Palermo
Syracuse bus station
No tags
Bus
Palermo Oreto Orsi
Syracuse bus station
No tags
Bus
Palermo Oreto Orsi
Syracuse bus station
No tags
Next departures for Palermo to Syracuse on September 28
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Terminal Bus Palermo
Syracuse bus station
Cheapest
Bus
Palermo Oreto Orsi
Syracuse bus station
Fastest
Bus
Terminal Bus Palermo
Syracuse bus station
No tags
Bus
Wifi
Toilet
Power outlets
Terminal Bus Palermo
Terminal Interbus
No tags
Bus
Terminal Bus Palermo
Syracuse bus station
No tags
Bus
Terminal Bus Palermo
Syracuse bus station
No tags
Bus
Palermo Oreto Orsi
Syracuse bus station
No tags
Bus
Palermo Oreto Orsi
Syracuse bus station
No tags
Next departures for Palermo to Syracuse on September 29
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Terminal Bus Palermo
Syracuse bus station
Cheapest
Bus
Palermo Oreto Orsi
Syracuse bus station
Fastest
Bus
Terminal Bus Palermo
Syracuse bus station
No tags
Bus
Wifi
Toilet
Power outlets
Terminal Bus Palermo
Terminal Interbus
No tags
Bus
Terminal Bus Palermo
Syracuse bus station
No tags
Bus
Terminal Bus Palermo
Syracuse bus station
No tags
Bus
Palermo Oreto Orsi
Syracuse bus station
No tags
Bus
Palermo Oreto Orsi
Syracuse bus station
No tags
Next departures for Palermo to Syracuse on October 1
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Terminal Bus Palermo
Syracuse bus station
Cheapest
Bus
Palermo Oreto Orsi
Syracuse bus station
Fastest
Bus
Terminal Bus Palermo
Syracuse bus station
No tags
Bus
Wifi
Toilet
Power outlets
Terminal Bus Palermo
Terminal Interbus
No tags
Bus
Terminal Bus Palermo
Syracuse bus station
No tags
Bus
Terminal Bus Palermo
Syracuse bus station
No tags
Bus
Palermo Oreto Orsi
Syracuse bus station
No tags
Bus
Palermo Oreto Orsi
Syracuse bus station
No tags
Last refresh of the prices: Today at 4:25 PM CEST.
Compare 2 ways to go from Palermo to Syracuse
We recommend taking the bus
Among the sustainable travel choices, the Bus stands out as a good way to reach Syracuse. The journey takes about 3 hours 20 minutes and with fares starting at just PEN 61, it presents an excellent value for a comfortable ride.
Passengers have shared positive feedback about their experiences, highlighting the punctuality and cleanliness of the buses. Many appreciated the friendly and helpful drivers who ensured a comfortable journey with convenient stops along the way. However, some noted minor inconveniences such as seating issues or discrepancies in ticket purchasing options from certain locations. Overall, travelers found it to be an efficient and pleasant service for reaching destinations like Siracusa.
Interbus Palermo Syracuse recent customer reviews
The journey was exellent!!the New, ❄️ bus with comfortable 🪑 and Professional driver.
5.0 out of 5 stars
Memo R.
Bus driver spoke on his mobile phone most of the trip.very unhelpful with organising loading of labs.he left Palermo depot with luggage doors still open-passengers had to tell him !
2.0 out of 5 stars
Fiona B.
Enjoyed - on time leaving. Improvements - hot on the bus/AC was barely turned on. Drive on his phone. No WiFi. No assigned seats. Also, the boarding was crazy. Men pushing in front of women. Making passengers open the bottom, etc. In other places, the driver always helped and kept everyone organized.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Palermo to Syracuse by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Palermo to Syracuse?
The cheapest bus tickets from Palermo to Syracuse start from PEN 61. The average price for this route is around PEN 72. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Palermo to Syracuse?
The average bus trip duration from Palermo to Syracuse is 3h 20m, covering a distance of 127 miles (204 km). The quickest bus can get you there in 3h 15m and is operated by Interbus Italy.
Which bus companies service the Palermo to Syracuse route?
Several major bus companies operate on this route with 8 buses available per day, including services from Interbus Italy, FlixBus.
What is the earliest and latest departure time for the bus from Palermo to Syracuse?
The earliest bus departs from Palermo to Syracuse at 8:00am. And the latest bus departs at 5:05pm.
What are the CO₂ emissions for the bus trip from Palermo to Syracuse?
A bus trip from Palermo to Syracuse generates an estimated 5.0985 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Palermo to Syracuse?
According to Busbud customers, the highest-rated bus company on this route is Interbus Italy, with an average rating of 4.0 out of 5 stars based on 810 reviews.
Which bus company has the best Wi-Fi from Palermo to Syracuse?
Based on reviews on Busbud, the bus company Interbus Italy has the best Wi-Fi rating with a score of 2.8.
Which bus company has the most timely service from Palermo to Syracuse?
According to Busbud traveler reviews, the most timely bus company on this route is Interbus Italy, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Palermo to Syracuse?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is Interbus Italy, with a cleanliness rating of 4.6 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
09/22
PEN 63
09/23
PEN 62
Today
PEN 62
09/25
PEN 62
09/26
PEN 62
09/27
PEN 62
09/28
PEN 63
09/29
PEN 62
The cheapest trip from Palermo to Syracuse was searched and found on Sep 24, 2026 with a price of PEN 62
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Palermo to Syracuse, as early as possible.
You can expect to pay from PEN 62 to PEN 117 for a bus ticket from Palermo to Syracuse based on the last 2 days. You can expect to find the cheapest price for the trip at PEN 62 which is on 2026-09-25.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Palermo to Syracuse?
The Bus is the cheapest travel choice for this destination
The cheapest trip from Palermo to Syracuse was searched and found on Sep 24, 2026 with a price of PEN 62
The Bus is the cheapest travel choice for this destination
