Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Camden (Walter Rand Transportation Center) | Bus station | Cheapest | ||||
 | Bus | Philadelphia Bus Station | Florence, SC | Fastest | ||||
| Bus | Philadelphia Bus Station | Bus station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Philadelphia Bus Station | Bus station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Philadelphia Bus Station | Bus station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Philadelphia Bus Station | Bus station | No tags |
Last refresh of the prices: Today at 5:17 PM EDT.
Compare 2 ways to go from Philadelphia to Florence
Among the sustainable travel choices, the Train stands out as a good way to reach Florence. The journey takes about 10 hours 55 minutes, and with fares starting at just CLP 94,388, it presents an excellent value for a comfortable ride.
Bus stations and stops in Philadelphia and Florence
Stops in Philadelphia
- A
Bus Station
1001 Filbert St, Philadelphia, PA 19107, USA - C
#2842 St.Vincent St
15th St Trolley Station, Philadelphia, PA 19102, USA - D
Island Av & Suffolk Av MBFS
3000 Island Ave, Philadelphia, PA 19153, USA - E
Independence Travel Center
Off of Race Street between 5th Street and, N 6th St, Philadelphia, PA 19106, USA - F
NRG SEPTA Station
3701 Broad St, Philadelphia, PA 19148, USA
Stops in Florence
- A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA - B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Compare bus companies
Frequently asked questions about travelling from Philadelphia, PA to Florence, SC, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Philadelphia to Florence?
The cheapest bus tickets from Philadelphia to Florence start from CLP 75,837. The average price for this route is around CLP 96,439. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Philadelphia to Florence?
The average bus travel time from Philadelphia to Florence is 13h 59m, covering a distance of 761 km. The quickest bus can get you there in 11h 15m and is operated by FlixBus.
Which bus companies service the Philadelphia to Florence route?
What are the earliest and latest departure times for the bus from Philadelphia to Florence?
The earliest bus departs from Philadelphia to Florence at 12:05am. And the latest bus departs at 10:30pm.
What are the CO₂ emissions for the bus trip from Philadelphia to Florence?
A bus trip from Philadelphia to Florence generates an estimated 19.002950000000002 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Philadelphia to Florence?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87585 reviews.
Which bus company has the best Wi-Fi from Philadelphia to Florence?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Philadelphia to Florence?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Philadelphia to Florence?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Philadelphia, PA to Florence, SC, US was searched and found on Jul 28, 2026 with a price of CLP 75,195To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Philadelphia, PA to Florence, SC, US, as early as possible.
You can expect to pay from CLP 75,195 to CLP 263,491 for a bus ticket from Philadelphia, PA to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at CLP 112,097 which is on 2026-08-01.
Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Philadelphia, PA to Florence, SC, US?
The Bus is the cheapest travel choice for this destination
