Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus
| Cherry Hill Mall | Bus station | Cheapest | ||||
 | Bus
| Philadelphia Bus Station | Florence, SC | Fastest | ||||
| Bus
| Cherry Hill Mall | Florence, SC | No tags | ||||
| Bus
| Philadelphia Bus Station | Bus station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus
| Philadelphia Bus Station | Bus station | No tags | ||||
| Bus
| Frazer - 56-40 Matthews Rd | Florence, SC | No tags | ||||
| Bus
| Philadelphia Bus Station | Bus station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus
| Frazer - 56-40 Matthews Rd | Bus station | No tags |
Last refresh of the prices: Last Saturday at 9:43 AM EDT.
Compare 2 ways to travel from Philadelphia to Florence
Among the sustainable travel choices, the Bus stands out as a good way to reach Florence. The journey takes about 13 hours 50 minutes and with fares starting at just CA$109, it presents an excellent value for a comfortable ride.
Bus stations and stops in Philadelphia and Florence
Stops in Philadelphia
- A
Bus Station
1001 Filbert St, Philadelphia, PA 19107, USA - C
#2842 St.Vincent St
15th St Trolley Station, Philadelphia, PA 19102, USA - D
Island Av & Suffolk Av MBFS
3000 Island Ave, Philadelphia, PA 19153, USA - E
Independence Travel Center
Off of Race Street between 5th Street and, N 6th St, Philadelphia, PA 19106, USA - F
NRG SEPTA Station
3701 Broad St, Philadelphia, PA 19148, USA
Stops in Florence
- A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA - B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Compare bus companies
Frequently asked questions about travelling from Philadelphia, PA, US to Florence, SC, US by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Philadelphia to Florence?
The cheapest bus tickets from Philadelphia to Florence start at CA$109. The average price for this route is around CA$139. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Philadelphia to Florence?
The average bus journey time from Philadelphia to Florence is 13h 50m, covering a distance of 761 km. The fastest bus gets you there in 11h 15m and is operated by FlixBus.
Which bus companies service the Philadelphia to Florence route?
What is the earliest and latest departure time for the bus from Philadelphia to Florence?
The earliest bus departs from Philadelphia to Florence at 00:05. And the latest bus departs at 23:25.
What are the CO₂ emissions for the bus trip from Philadelphia to Florence?
A bus trip from Philadelphia to Florence produces an estimated 19.017075000000002 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Philadelphia to Florence?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 88182 reviews.
Which bus company has the best Wi-Fi from Philadelphia to Florence?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Philadelphia to Florence?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Philadelphia to Florence?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Philadelphia, PA, US to Florence, SC, US was searched and found on 07 Oct 2026 with a price of CA$99To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Philadelphia, PA, US to Florence, SC, US as early as possible.
You can expect to pay from CA$99 to CA$186 for a bus ticket from Philadelphia, PA, US to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at CA$106, which is on 2026-10-10.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Philadelphia, PA, US to Florence, SC, US?
The Bus is the cheapest travel choice for this destination
